Newborn outcomes exposure to crack cocaine during pregnancy: a critical review / Recém-nascidos expostos ao crack durante a gestação: uma revisão crítica

Tatiane Britto da Silveira, Marina dos Santos, Ronan Adler Tavella, Rodrigo de Lima Brum, Edariane Menestrino Garcia, Adriane Netto de Oliveira, Ana Luíza Muccillo- Baisch, Flavio Manoel Rodrigues da Silva Júnior

Abstract


Crack cocaine is a psychotropic and neurotoxic drug with high prevalence of consumption, considerate a public health problem and identified as risk factors to human health. Crack cocaine use among women in reproductive age increased in few year and the literature of the neonatal exposure to this substance during pregnancy are limited. Thus, this critical review discusses the major newborn outcomes reported in original studies, highlighting neurologic abnormalities and malformations outcomes. Sixteen studies were included in this review. The main physiological outcome found in newborn exposure to crack cocaine during gestation were lower birth weight; preterm birth; growth restricted infants; lower 5-minute Apgar scores; small for gestational age; and, small head circumference and congenital malformations. There were several negative neurologic and outcomes were reported on the literature. Moreover, there were still no consensus and the main criticism in this area is the limited studies available.


Keywords


Illicit drugs, gestation, neonate.

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References


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DOI: https://doi.org/10.34117/bjdv6n3-115

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