Esteato-hepatite não alcoólica: uma síndrome em evidência / Non-Alcoholic Steatohepatitis: a syndrome in evidence

Authors

  • Isabelle Meneses da Ponte
  • Matheus Eugênio de Sousa Lima
  • Matheus Couto Furtado Albuquerque
  • Ana Flávia de Holanda Veloso
  • Tatiana Paschoalette Rodrigues Bachur

DOI:

https://doi.org/10.34119/bjhrv3n1-084

Keywords:

Doença hepática gordurosa não alcoólica, esteato-hepatite não alcóolica, obesidade, hepatologia, medicina interna, fígado gorduroso.

Abstract

O presente artigo apresenta uma revisão narrativa sobre epidemiologia, fisiopatologia, diagnóstico e tratamento da esteato-hepatite não alcóolica (EHNA). Nas últimas décadas, houve um crescimento na incidência mundial de obesidade e de doenças associadas. Dentre elas, destaca-se a EHNA, uma desordem metabólica com ampla variedade de apresentação, parte do espectro da doença hepática gordurosa não-alcóolica (DHGNA). A prevalência da DHGNA pode acometer até 25% da população em alguns estudos, sendo homens e hispânicos os grupos mais acometidos. A fisiopatologia da doença é complexa e multifatorial, com bases na obesidade, na resistência à insulina e na herança genética. Após diagnóstico, o manejo da EHNA consiste principalmente em mudanças de estilo de vida, tratamento da síndrome metabólica, farmacoterapia e manejo das complicações da cirrose hepática. Diante do aumento na prevalência de EHNA, é de grande interesse para a medicina a busca por melhores formas de obter sua detecção precoce, tratamento e controle de complicações. Essas questões são complexas e exigem uma abordagem multidisciplinar.

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Published

2020-02-13

How to Cite

PONTE, I. M. da; LIMA, M. E. de S.; ALBUQUERQUE, M. C. F.; VELOSO, A. F. de H.; BACHUR, T. P. R. Esteato-hepatite não alcoólica: uma síndrome em evidência / Non-Alcoholic Steatohepatitis: a syndrome in evidence. Brazilian Journal of Health Review, [S. l.], v. 3, n. 1, p. 1077–1093, 2020. DOI: 10.34119/bjhrv3n1-084. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/6855. Acesso em: 28 mar. 2024.

Issue

Section

Original Papers