Gut microbiota and probiotics as palliative care which supports physical activity in geriatric health / Microbiota e probiotic gut como cuidado paliativo que apoia a atividade física na saúde geriátrica

Vanessa Teixeira Müller, Michele Andrade de Brito, Andre Malina, Ângela Celeste Barreto de Azevedo, Ciro Jose Brito, Bianca Miarka

Abstract


Physical activity is considered a significant factor in the anti-aging process. In this sense, there is increasing scientific and clinical interest in the connections of nutrition and health as part of the aging progression. Studies have shown that there is an association between aging problems and gut microbiota performance. We performed this narrative review used the following databases: PubMed, Web of Science and Medline. The research was performed using the following keywords: [[[Aging] or [Senescence] or [Biological Aging] or [Aging, Biological] or [Aged] or [Aged, 80 and over] or [Life Expectancy] or [Length of Life]] in combination with [[microbiota] or [microbiotas] or [Microbiome] or [microbiomes] or [Human Microbiome] or [Human microbiomes] or [microbiomes, Human] or [Microbiome, Human]] not [[disease]]]. We selected analyzed 35 studies after search. The main results indicated that, associating care with the microbiota and physical activity practices in older adults can increase their chances of longevity. A lower prevalence of Bifidobacteria increase the chance of gastrointestinal infection with lower intestinal protection. The immunomodulatory properties of probiotics increase the prevention of infectious disease-related morbidity and mortality in older adults. There is still no research on the impact of the association between the care of the microbiota in older adults practicing physical activity. This review has the potential to save geriatric therapists time by providing comprehensive summaries of large information regarding the probiotics associated with physical practices used in palliative care in geriatric health.


Keywords


Microbiome, Microbiota, Aging, Prebiotics, Nutritional Sciences

Full Text:

PDF

References


Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., . . . Batto, J.-M. (2011). Enterotypes of the human gut microbiome. nature, 473(7346), 174.

Biagi, E., Nylund, L., Candela, M., Ostan, R., Bucci, L., Pini, E., . . . Franceschi, C. (2010). Through ageing, and beyond: gut microbiota and inflammatory status in seniors and centenarians. PloS one, 5(5), e10667.

Bosch, M. G., Espadaler, J. M., Méndez, M. S., Pérez, M. C., Farrán, A. C., Audivert, S. B., . . . Cuñé, J. C. (2011). Consumption of the probiotic Lactobacillus planctarum CECT 7315/7316 improves general health in the elderly subjects. Nutricion Hospitalaria, 26(3), 642-645.

Cani, P. D., & Delzenne, N. M. (2009). The role of the gut microbiota in energy metabolism and metabolic disease. Current Pharmaceutical Design, 15(13), 1546-1558.

Claesson, M. J., Cusack, S., O'Sullivan, O., Greene-Diniz, R., de Weerd, H., Flannery, E., . . . Fitzgerald, G. (2011). Composition, variability, and temporal stability of the intestinal microbiota of the elderly. Proceedings of the National Academy of Sciences, 108(Supplement 1), 4586-4591.

Costabile, A., Bergillos-Meca, T., Rasinkangas, P., Korpela, K., de Vos, W. M., & Gibson, G. R. (2017). Effects of Soluble Corn Fiber Alone or in Synbiotic Combination with Lactobacillus rhamnosus GG and the Pilus-Deficient Derivative GG-PB12 on Fecal Microbiota, Metabolism, and Markers of Immune Function: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Elderly (Saimes Study). Frontiers in Immunology, 8, 1443.

Cummings, J., & Macfarlane, G. (1997). Collaborative JPEN-Clinical Nutrition Scientific Publications Role of intestinal bacteria in nutrient metabolism. Journal of Parenteral and Enteral Nutrition, 21(6), 357-365.

Del Piano, M., Balzarini, M., Carmagnola, S., Pagliarulo, M., Tari, R., Nicola, S., . . . Pane, M. (2014). Assessment of the capability of a gelling complex made of tara gum and the exopolysaccharides produced by the microorganism Streptococcus thermophilus ST10 to prospectively restore the gut physiological barrier: a pilot study. Journal of Clinical Gastroenterology, 48, S56-S61.

Drago, L., Toscano, M., Rodighiero, V., De Vecchi, E., & Mogna, G. (2012). Cultivable and pyrosequenced fecal microflora in centenarians and young subjects. Journal of Clinical Gastroenterology, 46, S81-S84.

Ejtahed, H., Mohtadi-Nia, J., Homayouni-Rad, A., Niafar, M., Asghari-Jafarabadi, M., Mofid, V., & Akbarian-Moghari, A. (2011). Effect of probiotic yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis on lipid profile in individuals with type 2 diabetes mellitus. Journal of Dairy Science, 94(7), 3288-3294.

Evans, J. M., Morris, L. S., & Marchesi, J. R. (2013). The gut microbiome: the role of a virtual organ in the endocrinology of the host. Journal of Endocrinology, 218(3), R37-R47.

Gill, H. S., Rutherfurd, K. J., Cross, M. L., & Gopal, P. K. (2001). Enhancement of immunity in the elderly by dietary supplementation with the probiotic Bifidobacterium lactis HN019–. The American journal of clinical nutrition, 74(6), 833-839.

Graessler, J., Qin, Y., Zhong, H., Zhang, J., Licinio, J., Wong, M.-L., . . . Ehrhart-Bornstein, M. (2013). Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters. The Pharmacogenomics Journal, 13(6), 514.

Guillemard, E., Tondu, F., Lacoin, F., & Schrezenmeir, J. (2010). Consumption of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 reduces the duration of respiratory infections in the elderly in a randomised controlled trial. British Journal of Nutrition, 103(1), 58-68.

He, T., Harmsen, H. J., Raangs, G. C., & Welling, G. W. (2003). Composition of Faecal Microbiota of Elderly People. Microbial Ecology in Health & Disease, 15(4).

Hébuterne, X. (2003). Gut changes attributed to ageing: effects on intestinal microflora. Current Opinion in Clinical Nutrition & Metabolic Care, 6(1), 49-54.

Jeong, J.-J., Kim, K., Hwang, Y.-J., Han, M., & Kim, D.-H. (2016). Anti-inflammaging effects of Lactobacillus brevis OW38 in aged mice. Beneficial Microbes, 7(5), 707-718.

Macfarlane, S., Cleary, S., Bahrami, B., Reynolds, N., & Macfarlane, G. (2013). Synbiotic consumption changes the metabolism and composition of the gut microbiota in older people and modifies inflammatory processes: a randomised, double‐blind, placebo‐controlled crossover study. Alimentary Pharmacology & Therapeutics, 38(7), 804-816.

Malaguarnera, G., Leggio, F., Vacante, M., Motta, M., Giordano, M., Biondi, A., . . . Malaguarnera, M. (2012). Probiotics in the gastrointestinal diseases of the elderly. The Journal of Nutrition, Health & Aging, 16(4), 402-410.

Neto, J. V., De Melo, C. M., & Ribeiro, S. M. L. (2013). Effects of three-month intake of synbiotic on inflammation and body composition in the elderly: a pilot study. Nutrients, 5(4), 1276-1286.

Nicoletti, C. (2015). Age-associated changes of the intestinal epithelial barrier: local and systemic implications. Expert Review of Gastroenterology & Hepatology., 9(12), 1467-1469.

O'Hara, A. M., & Shanahan, F. (2006). The gut flora as a forgotten organ. EMBO Reports, 7(7), 688-693.

Ottman, N., Smidt, H., De Vos, W. M., & Belzer, C. (2012). The function of our microbiota: who is out there and what do they do? Frontiers in Cellular and Infection Microbiology, 2, 104.

Prakash, S., Rodes, L., Coussa-Charley, M., & Tomaro-Duchesneau, C. (2011). Gut microbiota: next frontier in understanding human health and development of biotherapeutics. Biologics: Targets & Therapy, 5, 71.

Rampelli, S., Candela, M., Severgnini, M., Biagi, E., Turroni, S., Roselli, M., . . . Brigidi, P. (2013). A probiotics-containing biscuit modulates the intestinal microbiota in the elderly. The Journal of Nutrition, Health & Aging, 17(2), 166-172.

Rymkiewicz, P. D., Heng, Y. X., Vasudev, A., & Larbi, A. (2012). The immune system in the aging human. Immunologic Research, 53(1-3), 235-250.

Sobhani, I., Tap, J., Roudot-Thoraval, F., Roperch, J. P., Letulle, S., Langella, P., . . . Furet, J. P. (2011). Microbial dysbiosis in colorectal cancer (CRC) patients. PloS one, 6(1), e16393.

Spaiser, S. J., Culpepper, T., Nieves Jr, C., Ukhanova, M., Mai, V., Percival, S. S., . . . Langkamp-Henken, B. (2015). Lactobacillus gasseri KS-13, Bifidobacterium bifidum G9-1, and Bifidobacterium longum MM-2 ingestion induces a less inflammatory cytokine profile and a potentially beneficial shift in gut microbiota in older adults: a randomized, double-blind, placebo-controlled, crossover study. Journal of the American College of Nutrition, 34(6), 459-469.

Steinhoff, U. (2005). Who controls the crowd? New findings and old questions about the intestinal microflora. Immunology Letters, 99(1), 12-16.

Tsuda, H., & Miyamoto, T. (2010). Guidelines for the evaluation of probiotics in food. Report of a joint FAO/WHO working group on drafting guidelines for the evaluation of probiotics in food Guidelines for the evaluation of probiotics in food. Report of a joint FAO/WHO working group on drafting guidelines for the evaluation of probiotics in food, 2002. Food Science and Technology Research, 16(1), 87-92.

Turchet, P., Laurenzano, M., Auboiron, S., & Antoine, J. (2003). Effect of fermented milk containing the probiotic Lactobacillus casei DN-114001 on winter infections in free-living elderly subjects: a randomised, controlled pilot study. The Journal of Nutrition, Health & Aging, 7(2), 75-77.

Turnbaugh, P. J., Hamady, M., Yatsunenko, T., Cantarel, B. L., Duncan, A., Ley, R. E., . . . Affourtit, J. P. (2009). A core gut microbiome in obese and lean twins. nature, 457(7228), 480.

van Beek, A. A., Sovran, B., Hugenholtz, F., Meijer, B., Hoogerland, J. A., Mihailova, V., . . . Hoeijmakers, J. H. (2016). Supplementation with Lactobacillus plantarum WCFS1 prevents decline of mucus barrier in colon of accelerated aging Ercc1−/Δ7 mice. Frontiers in Immunology, 7, 408.

WHO, W. H. O. (2015). World report on ageing and health. Geneva: World Health Organization.

Zaharoni, H., Rimon, E., Vardi, H., Friger, M., Bolotin, A., & Shahar, D. (2011). Probiotics improve bowel movements in hospitalized elderly patients—The proage study. The Journal of Nutrition, Health & Aging, 15(3), 215-220.

Zhang, Y.-J., Li, S., Gan, R.-Y., Zhou, T., Xu, D.-P., & Li, H.-B. (2015). Impacts of gut bacteria on human health and diseases. International Journal of Molecular Sciences, 16(4), 7493-7519.

Zhao, J., Tian, F., Yan, S., Zhai, Q., Zhang, H., & Chen, W. (2018). Lactobacillus plantarum CCFM10 alleviating oxidative stress and restoring the gut microbiota in D-galactose-induced aging mice. Food & Function, 9(2), 917-924.




DOI: https://doi.org/10.34119/bjhrv3n1-080

Refbacks

  • There are currently no refbacks.