Estudo retrospectivo da incidência de fatores de risco em portadores da doença arterial coronariana / Retrospective study of the incidence of risk factors in carriers of coronary arterial disease

Authors

  • Síntique Sepulvida dos Santos Raydan

Keywords:

Doença Arterial Coronária. Fatores de risco. Prevalência.

Abstract

Objetivou-se caracterizar o perfil do paciente portador de Doença Arterial Coronária (DAC) atendido no Instituto Paulista de Doenças Cardiovasculares, no que se refere aos fatores de risco. Para o estudo, cinquenta prontuários de pacientes com DAC foram selecionados aleatoriamente. Laudos de cateterismo (CATE), descrição de sintomas clínicos, e conduta terapêutica, foram coletados para caracterização clínica dos pacientes. O percentual dos fatores de risco obtidos por análise retrospectiva da descrição médica, durante o diagnóstico de DAC, apontou: sedentarismo (92%); Hipertensão Arterial Sistêmica (HAS) (90%); Dislipidemia (DLP) (82%); Diabetes Mellitus (DM) (50%); tabagismo (14%); etilismo (6%); história familiar (14%); e obesidade (18%). Constatou-se uma alta prevalência de fatores de risco para DAC e sobreposição de dois ou mais fatores modificáveis, mostrando a necessidade do incremento de medidas preventivas, a fim de resultar, em uma menor taxa de morbi-mortalidade cardiovascular.

References

AIRD, William. Phenotypic Heterogeneity of the Endothelium I. Structure, Function, and Mechanisms. Circulation Research, Dallas, v.100, p. 158-173, feb. 2007. Avaliable from: <http://circres.ahajournals.org/content/100/2/158/tab-article-info>. Access on 28 nov. 2017.

AIRD, William. Phenotypic Heterogeneity of the Endothelium II. Representative Vascular Beds. Circulation Research, Dallas, v.100, p. 174-190, feb. 2007. Avaliable from: <http://circres.ahajournals.org/content/100/2/174.long#ref-21>. Access on 28 nov. 2017.

ALBERTI, Mathew et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention. Circulation, v. 120, n. 16, p. 1640-1645, oct. 2009. Available from:< https://www.ncbi.nlm.nih.gov/pubmed/19805654>. Access on 28 jan. 2018.-and-follow-up>. Access on 15 feb 2018.

ANTMAN, Elliott. ST-Segment Elevation Myocardial Infarction. BONOW, Robert et al. In: Braunwald’s heart disease: a textbook of cardiovascular medicine. ed. 9. Philadelphia: Elsevier Saunders, 2012. cap. 54, p. 1087-1109.

ANVERSA, Pierro; KAJSTURA, Jan and LERI, Annarosa. Cardiovascular Regeneration and Tissue Engineering. BONOW, Robert et al. In: Braunwald’s heart disease: a textbook of cardiovascular medicine. ed. 9. Philadelphia: Elsevier Saunders, 2012. cap. 11, p. 99-106.

BAE, Hojae et al. Building Vascular Networks. Science translational medicine, v. 4, n. 160, p 1-23, nov. 2012. Avaliable from: <https://www.ncbi.nlm.nih.g ov/pmc/articles/PMC3569029/pdf/nihms439090.pdf>. Access on 28 nov. 2017.

BAILEY, Clifford and DAY, Caroline. Glycaemic memory. The British Journal of Diabetes and Vascular Disease, v. 8, p. 242-247, nov. 2008. Avaliable from: <http://journals.sagepub.com/doi/abs/10.1177/1474651408098784>. Access on 29 abr. 2018.

BEHRENDT, Dominik and GANZ Peter.Endothelial Function: From Vascular Biology to Clinical Applications. The American Journal of Cardiology, Boston, v. 90, n. 10, p. 40-48, nov. 2002. Avaliable from: <https://www.ajconline.org/article/S0002-9149(02)02963-6/fulltext >. Access on 22 nov. 2017.

BONETTI, Piero; LERMAN Lilach, and LERMAN Almir. Endothelial dysfunction: a marker of atherosclerostic risk. Arteriosclerosis, Thrombosis, and Vascular Biology. v. 23, n. 5, p. 168-175, dec. 2003. Avaliable from:<https://www.ncbi.nlm.nih.gov/pubmed/12588755>. Access on 27 nov. 2017.

BORGES, Juliana. Características estruturais e funcionais das células endoteliais. 2011. 44 f. Tese (Mestrado em Ciência Animal da Escola de Veterinária e Zootecnia) - Universidade Federal de goiás escola de veterinária e zootecnia, Goiânia, 2012.

BOURBON, Mafalda et al. Sabe como prevenir Doenças Cardiovasculares?.Instituto Nacional de Saúde Doutor Ricardo Jorge. Disponível em: <http://www.cardiometro.com.br/>. Acesso em 30 abr 2018.

BOVET, Pascal. Editorial: The cardiovascular disease epidemic: global, regional, local. Tropical medicine and International Health, Lausanne, v 7, n. 9, p 717-721, sept. 2002. Available from: <https://pdfs.semanticscholarorg/abd8/49f5a7852b02b38 b377160b99e586d8290a2.pdf>. Access on: 20 nov. 2017.

BROWNLEE, Michael. The Pathobiology of Diabetic Complications: A Unifying Mechanism. Diabetes, v.54, n. 6, p. 1615 – 1625, jun. 2005. Avaliable from: <http://diabetes.diabetesjournals.org/content/54/6/1615.long>. Access on 29 abr 2018

CAMPOS, Shirley. Medicina Avançada. Moléculas de adesão. Disponível em: <http://www.drashirleydecampos.com.br/noticias/279 >. Acesso em 30 abr 2018.

CANNON, Christopher and BRAUNWALD, Eugene. Unstable Angina and Non–ST Elevation Myocardial Infarction. BONOW, Robert et al. In: Braunwald’s heart disease: a textbook of cardiovascular medicine. ed. 9. Philadelphia: Elsevier Saunders, 2012. cap. 56, p. 1178-1201.

CARDEÑA, Guilhermo et al. Biomechanical activation of vascular endothelium as a determinant of its functional phenotype. Proceedings of the National Academy of Sciences, v. 98, n. 8, p. 4478-4485. Avaliable from:<https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31860/>. Access on 27 nov. 2017.

CARVAJAL, Carlos. El endotelio: estructura, función y disfunción endotelial. Medicina legal de Costa Rica, Heredia, v. 34, n. 2, p. 90-100, dec. 2017. Disponible en: <http://www.scielo.sa.cr/scielo.php?script=sci_arttext&pid=S1409-0015201700020009 0>. Acceso em 10 dec. 2017.

CARVALHO, Carolina et al. Associação entre fatores de risco cardiovascular e indicadores antropométricos de obesidade em universitários de São Luís, Maranhão, Brasil Ciência e Saúde Coletiva, v. 20, n. 2, p. 479-490, feb. 2015. Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S14138123201500020047&lng

CENTERS OF DISEASE CONTROL AND PREVENTION- CDC. National Center for Health Statistics. Avaliable from: <https://www.cdc.gov/nchs/hus/index.htm>. Access on: 29 abr 2018.

CHEN Wei, BACANAMWO, Methode; and HARRISON, David. Activation of p300 Histone Acetyltransferase Activity Is an Early Endothelial Response to Laminar Shear Stress and Is Essential for Stimulation of Endothelial Nitric-oxide Synthase mRNA Transcription. Journal of Biological Chemistry, v. 283, n. 24, p. 16293–16298, jun. 2008. Avaliable from:<https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423243/>. Access on 28 nov. 2017.

CHI, Jen et al. Endothelial Cell Diversity Revealed by Global Expression Profiling. Proceedings of the National Academy of Sciences of the United States of America, Washington, v.100, n. 19, p. 10623-10628, sept. 2003. Avaliable from: . Access on 28 nov. 2017.cle/pii/0735109794906270?via%3Dihub>. Access on 22 nov. 2017.

CREAGER, Mark; LIBBY, Peter. Peripheral Artery Diseases. BONOW, Robert et al. In: Braunwald’s heart disease: a textbook of cardiovascular medicine. e 9. Philadelphia: Elsevier Saunders, 2012. cap. 61, p. 1338-1356.

DIOGO, Catia et al. Cardiac mitochondrial dysfunction during hyperglycemia—The role of oxidative stress and p66Shc signaling. The International Journal of Biochemistry & Cell Biology, v. 45, n. 1, p.114– 122, jan. 2013. Avaliable from: <https://www.ncbi.nlm.nih.gov/pubmed/22776741>. Access on 29 abr 2018.

DIRETRIZES BRASILEIRAS DE HIPERTENSÃO ARTERIAL. Arquivos Brasileiros de Cardiologia, São Paulo, v. 89, n. 3, p. 24-79, sept. 2007. Available from <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2007001500012&I

DIXON, Jesse et al. Chromatin Architecture Reorganization during Stem Cell Differentiation. Reorganização da arquitetura de cromatina durante a diferenciação de células-tronco. Nature, London, v. 528, n. 7539, p. 331-336, feb. 2015. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515363/>. Access on 28 nov. 2017.

DUNN, Jessilyn; THABET, Salim and JO, Hanjoong. Flow-Dependent Epigenetic DNA Methylation in Endothelial Gene Expression and Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology, v. 35, n. 7, p. 1562–1569, may. 2015. PMC. Web. 14 May 2018. Avaliable from:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC475.Access on 30 jan. 2018.

EGGER, Gerda et al. Epigenetics in human disease and prospects for epigenetic therapy. Nature Publishing Group, Los Angeles, v. 429, p. 457-463, may. 2009. Avaliable from: <https://www.nature.com/articles/nature02625>. Access on 28 nov. 2017.

EL-OSTA Assam, et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. Journal of Experimental Medicine, v. 205, n. 10, p. 2409–2417, sep. 2008. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556800/ >. Access on 29 abr 2018

ESPER, Rocardo et al. Endothelial dysfunction: a comprehensive appraisal, Cardiovascular Diabetology, v. 5, n. 4, p. 1-18, feb. 2006. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1434727/>. Access on 28 nov. 2017.

EVANS, Howard and MARTIN, Patricia. Gap junctions: structure and function (Review). Molecular Membrane Biology, v. 2, p. 121-136, jul. 2009. Avaliable from: <https://www.tandfonline.com/doi/abs/10.1080/09687680210139839>. Access on 28 nov. 2017.

FAREVO, Gaia et al. Endothelium and Its Alterations in Cardiovascular Diseases: Life Style Intervention. BioMed Research International, Brescia, v. 2014, p.1-28, feb. 2014. Avaliable from: <https://www.hindawi.com/journals/bmri/2014/801896/cta/>. Access on 28 nov. 2017.

FELS, Johannes et al. Nanomechanics of Vascular Endothelium. Cell and Tissue Research, v. 355, n.3, p. 727–737, mar. 2014. PMC. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972433/ >. Access on 28 nov. 2017.

FERREIRA, Celma and FERREIRA, Márcia. Características epidemiológicas de pacientes diabéticos da rede pública de saúde: análise a partir do sistema HiperDia. Arquivos Brasileiros de Endocrinologia e Metabologia, v. 53, n. 1, p. 80-86, feb. 2009. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid

FISH, Jason et al. Hypoxic Repression of Endothelial Nitric-oxide Synthase Transcription Is Coupled with Eviction of Promoter Histones. Jounal of biological chemistry, v. 285, n. 2, p. 810-826, jan. 2010. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/

FLETCHER, Daniel; and MULLINS, Dyche. Cell Mechanics and the Cytoskeleton. Nature, v. 463, n. 7280, p. 485–492, jan. 2010. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851742/ >. Access on 28 nov. 2017.

FURCHGOTT, Robert. Endothelium-Derived Relaxing Factor: Discovery, Early Studies, and Identification as Nitric Oxide. Bioscience Reports, New York, v. 19, n. 4, p. 235-251, mar. 1998. Avaliable from: <https://www.nobelpr ize.org/nobel_prizes/medicine/laur eates/1998/furchgott-lecture.pdf>. Access on 22 nov. 2017.

GERALDES, Pedro and KING, George. Activation of protein kinase C isoforms and its impact on diabetic complications. Circulation Research, v. 106, n. 8, p. 1319–1331, apr. 2010. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877591/>. Access on 29 abr 2018.

GIACCO, Ferdinando and BROWNLEE, Michael. Oxidative stress and diabetic complications. Circulation Reserarch, v. 107, n. 9, p. 1058-1079, oct. 2010. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877591/>. Access on 29 abr 2018.

GIROTTO, Edmarlon et al. Prevalência de fatores de risco para doenças cardiovasculares em hipertensos cadastrados em unidade de saúde da família. Health Sciences, v. 31, n. 1, p. 77-82, jun. 2009. Available from:<http://periodicos.uem.br/ojs/index.php/ActaSciHealthSci/article/view/4492/0>. Access on 30 dec. 2017.

GORI, Tomaso et al. Endothelium and haemorheology. Annali dell'Istituto superiore di sanita, Siena, v. 43, n. 2, p. 124-129, feb. 2007. Avaliable from: <https://www.researc hgate.net/publication/6203126_Endothelium_and_haemorheology>. Access on 28 nov. 2017.

GROSS, Jorge. et al. Diabetes Melito: Diagnóstico, Classificação e Avaliação do Controle Glicêmico. Arquivos Brasileiros de Endocrinologia e Metabologia, v. 46, n. 1, p. 16-26, feb. 2002. Disponível em: http://www.scielo.br/scielo.php?script=sci_artte. Acesso em 28 jan. 2018.

HASSAN, Othman et al. Arterial identity of endothelial cells is controlled by local cues. Developmental Biology, London, v. 237, n. 2, p. 398-409, sept. 2001. Avaliable from: https://www.ncbi.nlm.nih.gov/pubmed/11543623>. Access on 28 nov. 2017.

HECKMANN, Wolfgang and SILVEIRA, Camila. O álcool e suas consequências, uma abordagem multicor. In: O álcool e suas consequências, uma abordagem multiconcenitual. Barueri: Minha Editora, 2009. cap.3, p.67-87.

HERRMANN, Harald et al. Intermediate filaments: from cell architecture to nanomechanics. Nature Reviews Molecular Cell Biology, v. 8, n. 7, p. 562-73, jul 2007. Avaliable from: < https://www.nature.com/articles/nrm2197 >. Access on 28 nov. 2017.

HOWLETT, Jonathan. Manual MSD. Considerações gerais sobre a Doença Arterial Coronariana. Disponível em: < https://www.msdmanuals.com/ptbr/casa/dist%C3%BA

i_arttext&pid=S1983-14472010000100018&lng=en&nrm=iso>. Access on 15 feb 2018.

INSUL, Wilian. The Pathology of Atherosclerosis: Plaque Development and Plaque Responses to Medical Treatment. The American Journal of medicine, v. 122, n. 1, p. 514 – 530, jan. 2009. Available from: <https://www.amjmed.com/article/S0002-9343(08)01017-6/fulltext>. Access on 15 feb 2018.

INTERNATIONAL DIABETES FEDERATION- IDF. IDF Diabetes Atlas. 8 ed. São Paulo: Atlas, 2017.

JESUS, Wiliam et al. O Paradoxo da Vida Aeróbica. Journal of Amazon Health Science, v. 1, n. 1, p.11-35, jul. 2015. Avaliable from: <http://scholar.googleusercontent.com/scholar?q=cache:mmBhMHCN7WEJ:scholar.google.com/&hl=pt-BR&as_sdt=0,5>. Access on 29 abr 2018.

KAIKKONEN, Minna et al. Control of VEGF-A transcription programs stopping and genomic compartmentalization. Nucleic Acids Research, Oxford, v. 42, n. 20, p. 12570-12584, nov. 2014. Avaliable from: < >. Access on 28 nov. 2017.

KAISER, Nurit et al. Differential regulation of glucose transport and transporters in smooth muscle and vascular endothelial cells. Diabetes, v.42, n. 1, p. 80 – 89, jan. 1993. Avaliable from: <https://www.ncbi.nlm.nih.gov/pubmed/7678404>. Access on 29 abr 2018

KIETADISORN, Rinrada; JUNI, Rio. Juni; MOENS, An. Tackling endothelial dysfunction by modulating NOS uncoupling: new insights into its pathogenesis and therapeutic possibilities. Jounnal American Physiol Endocrinol Metabolism, Maastricht, v. 302, n. 5, p. 481–495, mar 2012. Avaliable from: <https://www.physiology.org/do i/10.1152/ajpendo.00540.2011>. Access on 22 nov. 2017.

KOHLHAAS, Michael et al. Elevated cytosolic Na + increases the mitochondrial formation of reactive oxygen species in failing cardiac myocytes. Circulation, v. 121, n.14, p. 1606-1613, apr. 2010. Avaliable from: <http://diabetes.diabetesjournals.org/content/54/6/1615.long>. Access on 29 abr 2018

KRONLAGE, Cornelius et al. Feeling for Filaments: Quantification of the Cortical Actin Web in Live Vascular Endothelium. Biophysical Journal, v. 109, n. 4, p. 687–698, aug. 2015. Avaliable from: <https://www.ncbi.nlm.nih.gov/pubmed/26287621>. Access on 28 nov. 2017.

LEMOS, Karine et al. Prevalência de fatores de risco para Síndrome Coronariana aguda em pacientes atendidos em uma emergência. Revista Gaúcha de Enfermagem, v. 31, n. 1, p. 129-135, mar. 2010. Available from :<http://www.scielo.br/scielo.php?script=sc

LERMAN, Amir and ZEIHER, Andreas. Endothelial function: cardiac events. Circulation. v. 111, n. 3, p. 363-368, jan. 2005. Avaliable from:<https://www.ncbi.nlm.nih.gov/pubmed/15668353>. Access on 27 nov. 2017.

LIBBY, Peter. The Vascular Biology of Atherosclerosis. BONOW, Robert et al. In: Braunwald’s heart disease: a textbook of cardiovascular medicine. e 9. Philadelphia: Elsevier Saunders, 2012. cap. 43, p. 897-912.

LUPU, Cristina et al. Tissue Factor-Dependent Coagulation Is Preferentially Up-Regulated within Arterial Branching Áreas in a Baboon Model of Escherichia coli Sepsis. American Journal of Pathology, Okalaboma, v. 167, n. 4, p. 1161-1172, oct. 2005. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1415276/pdf/JPATH16 7001161.pdf>. Access on 28 nov. 2017.

MAN, Hon-Sum Jeffrey et al. Epigenetic determinants of cardiovascular gene expression: vascular endothelium. Epigenomics, v. 8, n. 7, p. 1750-1911, jun. 2016. Avaliable from:< https://www.futuremedicine.com/doi/10.2217/epi-2016-0012>. Access on 28 nov. 2017.

MANSUR, Antonio et al. Diretrizes de doença coronariana crônica angina estável. Arquivos Brasileiros de Cardiologia, v. 83, n. 2, p. 20-43, sept. 2004. Available from:<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2004002100

MARCELO, Kathrina; LAUREN, Goldie and HIRSCHI, Karen. Regulation of Endothelial Cell Differentiation and Specification. Circulation Research, New Haven, v. 112, n. 9, p. 1272-1287, abr. 2013. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/P MC3768127/pdf/nihms474442.pdf>. Access on 28 nov. 2017.

MARIAPPAN Nithya et al. Mitochondrial Lesion by TNF: a link between mitochondrial complex I activity and left ventricular dysfunction. Free Radical Biology and Medicine, v. 46, n. 4, p. 462-470, feb. 2009. Avaliable from: <https://www.ncbi.nlm.nih.gov/pubmed/19041937>. Access on 28 nov. 2017.

MARTINEZ, Shannalee; GAY, Maresha and ZHANG, Lubo. Epigenetic mechanisms in heart development and disease. Drug Discovery Today, v. 20, n. 7, p. 799-811, jul. 2015. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4492921/>. Access on 28 nov. 2017.

MATHERS, Colin; LOPEZ, Alan and MURRAY, Christopher. “The Burden of Disease and Mortality by Condition: Data, Methods, and Results for 2001.” In: LOPEZ, Alan et al. In Global Burden of Disease and Risk Factors. 2006. 3, 54-93. Avaliable from: <https://www.ncbi.nlm.nih.gov/books/NBK11808/ >. Access on: 28 abr 2017.

MELLI, Mahmoudi et al. Statins Use a Novel Nijmegen Breakage Syndrome-1–Dependent Pathway to Accelerate DNA Repair in Vascular Smooth Muscle Cells. Circulation Research, v. 103, p. 717-725, sept. 2008. Avaliable from: <http://circres.ahajournals.org/content/103/7/717#ref-3>. Access on 13 abr. 2018.

MINAMI, Takashi and AIRD, William. Endothelial Cell Gene Regulation. Trends in Cardiovascular Medicine, Boston, v.15, n. 5, p.174-184, jul. 2005. Avaliable from: <https://www.tcmonline.org/article/S1050-1738(05)00083-6/fulltext>. Access on 27 nov. 2017.

MIQUEROL, Lucile; LANGILLE, Lowell and NAGY, Andras. Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression. The Company of Biologists, Cambridge, v. 127, p. 3941-3946, jul. 2000. Avaliable from: <http://dev.biologists.org/content/develop/127/18/3941.full.pdf>. Access on 28 nov. 2017.

MONTERA, Marcelo et al. II Diretriz Brasileira de Insuficiência Cardíaca Aguda. Arquivos Brasileiros de Cardiologia, São Paulo, v. 93, n. 3, p. 2-65, 2009. Disponível em:<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066782X2009001900001&lng=en&nrm=iso>. Acesso em 12 jan 2018.

NATHAN David et al. Research Group of the Diabetes Study Control and Complications/ Epidemiology of Diabetes Interventions and Complications (DCCT / EDIC). Intensive treatment of diabetes and cardiovascular disease in patients with type 1 diabetes. New England Journal of Medicine, v. 353, n. 25, p. 2643-2653, dec. 2005. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637991.ndle/10665/43588/9241594934_eng.pdf?sequenc=>. Access on 29 abr 2018.

NEWBY, Kristin and DOUGLAS, Pamela. Cardiovascular Disease in Women. BONOW, Robert et al. In: Braunwald’s heart disease: a textbook of cardiovascular medicine. e 9. Philadelphia: Elsevier Saunders, 2012. cap. 81, p. 1757-1767.

ng=en&nrm=iso>. Access on 15 may. 2018.

NICOLAU, José et al. Guidelines for Unstable Angina and Non-STSegment Elevation Myocardial Infarction of the Brazilian Society of Cardiology (II Edition, 2007). Arquivos Brasileiros de Cardiologia, v. 89, n. 4, p. 89-131, oct. 2007. Available from:< https://www.ncbi.nlm.nih.gov/pubmed/14503977>. Access on 28 jan. 2018.

NISKANEN, Henri et al. Endothelial cell differentiation is encompassed by changes in long range interactions between inactive chromatin regions. Nucleic Acids Research, Oxford, v. 46, n. 4, p. 1724-1740, dec. 2017. Avaliable from: . Access on 28 nov. 2017.

NORDSBORG, Nikolai et al. Muscle interstitial potassium kinetics during intense exhaustive exercise: effect of previous arm exercise. American Journal of Physiology-Regulatory - Integrative and Comparative Physiology, v. 285, n. 1, p. 143-148, jul. 2003. Avaliable from: <https://www.ncbi.nlm.nih.gov/pubmed/12663256 >. Access on 28 nov. 2017.

OLBRICH, Sandra. et al. Sedentarismo: prevalência e associação de fatores de risco cardiovascular. Revista Ciência em Extensão, v.5, n. 2, p.30-41, abr. 2009. Available from:<http://periodicos.uem.br/ojs/index.php/ActaSciHealthSci/article/view/4492/0>. Access on 30 dec. 2017.

ORGANIZAÇÃO PAN-AMERICANA DE SAÚDE - OPAS. Doenças Cardiovasculares. Disponível em: <http://www.paho.org/bra/index.php?option=com_content&vie w=articl e&id=5253:doencas-cardiovasculares&Itemid=839>. Acesso em: 30 abr 2018.

ORGANIZAÇÃO PAN-AMERICANA DE SAÚDE - OPAS. Doenças Cardiovasculares. Disponível em: <http://www.paho.org/bra/index.php?option=com_content&vie w=articl e&id=5253:doencas-cardiovasculares&Itemid=839>. Acesso em: 30 abr 2018.

PAIVA, Sérgio et al. Comportamento de Variáveis Cardíacas em Animais Expostos à Fumaça de Cigarro. Arquivos Brasileiros de Cardiologia, v. 81, n,3, p. 221-4, oct. 2003. Available from:< http://publicacoes.cardiol.br/abc/2003/8103/81030002.pdf >. Access on 28 jan. 2018.

PASSERINI, Anthony et al. Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta. Proceedings of the National Academy of Sciences of the United States of America Los Angeles, Los Angeles, v. 101, n. 8, p. 2482-2487, feb. 2004. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC356976/>. Access on 28 nov. 2017.

PASSOS, Valéria; ASSIS, Tiago and BARRETO, Maria. Hipertensão arterial no Brasil: estimativa de prevalência a partir de estudos de base populacionalHypertension in Brazil: estimates from population-based prevalence studies. Epidemiologia e Serviços de Saúde, Brasília, v. 15, n. 1, p. 35-45, mar. 2006. Disponível em <http://scielo.iec.gov.br/scielo.php?script=sci_arttext&pid=S167949742006000100003&lng=pt&nrm=iso>. Acesso em 14 maio 2018.

PATEL-HETT, Sunita and D'AMORE, Patricia. Signal Transduction in Vasculogenesis and Developmental Angiogenesis. The International Journal of Developmental Biology, Boston, v. 55, p. 353-363, jun. 2011. Avaliable from: <https://www.ncbi. nlm.nih.gov/pmc/articles/PMC4075038/pdf/nihms-602913.pdf>. Access on 28 nov. 2017.PMC2801283/>. Access on 13 abr. 2018.

PEIXOTO, Maria do Rosário; BENÍCIO, Maria Helena. The relationship between body mass index and lifestyle in a Brazilian adult population: a cross-sectional survey. Caderno de Saúde Pública, v. 23, n. 11, p. 2694-2704, 2007.Available from:< http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2007001100017>. Access on 30 apr. 2018.

PIEGAS, Leopoldo et al. Risk factors for myocardial infarction in Brazil. American Heart Journal, v.146, n. 2, p. 331-338, aug. 2003. Avaliable from:< https://www.ahjonline.com/article/S0002-8703(03)00181-9/fulltext>. Access on 22 nov. 2017

PRAY, Leslie. The Scientist. Epigenetics: Genome Meet your environment. Disponível em: <https://www.the-scientist.com/?articles.view/articleNo/15772/title/Epigenetics--Genome--Meet-Your-Environment/>. Acesso em 30 abr 2018.

REDDY, Karan et al. Evidence that selective endothelial dysfunction may occur in the absence of angiographic or ultrasound atherosclerosis in patients with risk factors for atherosclerosis. Journal of the American College of Cardiology, Cleveland, v. 23, n. 4, p. 833-883, mar. 1994. Avaliable from: https://www.sciencedirect.com/scien ce/arti.> Access on 17 nov. 2017

RISAU, Werner et al. Vasculogenesis and angiogenesis in embryonic bodies derived from embryonic stem cells. The Company of Biologists, Great Britain, v. 102, n. 3, p. 471-478, mar. 1988. Avaliable from: <http://dev.biologists.org/content/de velop/102/3/471.full.pdf S0006295210004399>. Access on 28 nov. 2017.

SCHÄCHINGER, Volker; BRITTEN, Martina and ZEIHER, Andreas. Prognostic impact of coronary vasodilator dysfunction on adverse long- term outcome of coronary heart disease. Circulation, v. 101, n. 16, p. 1899–1906, abr. 2000. Avaliable from:<http://circ.ahajournals.org/content/101/16/1899.long >. Access on 27 nov. 2017.

SCHEIBMEIR, Heath et al. A review of free radicals and antioxidants for critical care nurses. Intensive Critical Care Nursing, v. 21, n. 1, p. 24-28, feb. 2005. Avaliable from: < https://www.intensivecriticalcarenursing.com/article/S0964-3397(04)00085-0/fulltext>. Access on 29 abr 2018.

SIEBEL, Andrew; FERNANDEZ, Ana and EL-OSTA, Assam. Glycemic memory associated epigenetic changes. Biochemical Pharmacology, v. 80, n. 12, p. 1853-1859, dec. 2010. Avaliable from: <https://www.sciencedirect.com/science/article/abs/pii/

SILVA, João; CARLOTA, Maria. Endotelio arterial e aterotrombogenese II disfuncao endotelial e desenvolvimento. Revista Portuguesa de Cardiologia, Lisboa, v. 25, n. 12, p.1159–86, dec. 2006. Disponível em: <http://www.hem orreologia.com/docu mentos/endotelio_arterial_aterogeneses_II.pdf>. Acesso em: 19 nov. 2017.

SIMIONESCU, Maia; SIMIONESCU Nicolae and PALADE George. Segmental differentiations of cell junctions in the vascular endothelium. Arteries and veins. The Journal of Cell Biology, v. 68, n. 3, p. 705 -723, mar. 1976. Avaliable from: . Access on 28 nov. 2017.

SIQUEIRA, Antonela; ABDALLA, Dulcinéia and FERREIRA, Sandra. LDL: da síndrome metabólica à instabilização da placa aterosclerótica. Arquivos Brasileiros de Endocrinologia e Metabologia, v. 50, n. 2, p. 334-343, apr. 2006. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S000427302006000200020&lng=en&nrm=iso>. Access on 28 mar. 2018.

SOCIEDADE BRASILEIRA DE CARDIOLOGIA- SBC. Cardiômetro. Disponível em: <http://www.cardiometro.com.br/>. Acesso em 30 abr 2018.

SOCIEDADE BRASILEIRA DE HIPERTENSÃO- SBH. Perguntas Frequêntes: o que é hipertensão. Disponível em: <http://www.sbh.org.br/geral/faq.asp>. Acesso em 30 abr 2018.

SOCIEDADE DE CARDIOLOGIA DO ESTADO DE SÃO PAULO- SOCESP. Prevenção. Disponível em: <http://www.socesp.org.br/prevencao/blog-do-coracao/destaque/?p=654&c=9-verdades-e-1-mentira-sobre-doencascardiovasculares-#.WuyuPogvy00>. Acesso em: 19 jul. 2014.

SPOSITO, Andrei et al. IV Diretriz Brasileira sobre Dislipidemias e Prevenção da Aterosclerose: Departamento de Aterosclerose da Sociedade Brasileira de Cardiologia. Arquivos Brasileiros de Cardiologia, v. 88, n. 1, p. 2-19, apr. 2007. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066782X2007000700002&lng=en&nrm=iso>. Access on 22 mar. 2018.

TAKANO, Hiromichi et al. Spreading dilatation in rat mesenteric arteries associated with calcium-independent endothelial cell hyperpolarization. Journal of Physiology, Bath, v. 556, n. 3, p. 887–903, may. 2004. Avaliable from: <https://www.ncbi.nlm.nih.gov /pmc/articles/PMC1665000/pdf/tjp0556-0887.pdf >. Access on 22 nov. 2017.

TARBELL et al. Fluid Mechanics, Arterial Disease, and Gene Expression. Annual Review of Fluid Mechanics, v. 46, p. 591–614, jan. 2014. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211638/ >. Access on 28 nov. 2017.

THORIN, Eric. 2011. Vascular disease risk in patients with hypertriglyceridemia: endothelial progenitor cells, oxidative stress, accelerated senescence, and impaired vascular repair. Canadian Journal of Cardiology, Quebec, v. 27, n. 5, p. 538–540, setp.-oct. 2011. Avaliable from: <https://www.onlinecjc.ca/article/S0828-282X(11)00254-6/fulltext>. Access on 20 nov. 2017.

THORIN, Eric; and TRESCASES, Nathalie. 2009. Vascular endotelial ageing, heartbeat after heartbeat. Cardiovascular Ressearch, Quebec, v. 84, n. 1, p. 24–32, oct. 2009. Avaliable from: <https://academic.oup.com/cardiovascres/article/84/1/24/283263>. Access on 28 nov. 2017.

TRIGLLE, Chris et al. The endothelium: influencing vascular smooth muscle in many ways. Canadian Journal of Physiology and Pharmacology, Doha, v. 90, n. 6, p. 713-738, may. 2012. Avaliable from: <http://www.nrcresearchpress.com/doi/full /10.1139/y2012-073#.Wu6Al4gvy02>. Access on 22 nov. 2017.

UK PROSPECTIVE DIABETES STUDY GROUP (UKPDS). Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). The Lancet, v. 352, n. 9131, p. 837-853, sep. 1998. Avaliable from: <http://journals.sagepub.com/doi/abs/10.1177/14. Access on 22 nov. 2017.

UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL- UFRGS. Projeto LipoCardium. Disponível em: <http://www.ufrgs.br/fisiologiacelular/site/lipoc.htm>. Acesso em 30 abr 2018.

VAZQUEZ Jesús; KAMEI Makoto and WEINSTEIN Brant. Molecular distinction between arteries and veins. Cell and Tissue Research, v. 314, n. 1, p. 43 -59, oct. 2003. Avaliable from: <https://www.ncbi.nlm.nih.gov/pubmed/14505031>. Access on 28 nov. 2017.

VILODRE, Luiz et al. Endometrial response to a cyclic regimen of percutaneous 17beta-estradiol and low-dose vaginal micronized progesterone in women with mild-to-moderate hypertension. Gynecological Endocrinology, v. 17, n. 4, p. 323–328, aug. 2003. Available from: <https://www.ncbi.nlm.nih.gov/pubmed/14503977>. Access on 15 feb 2018.

VOGHEL, Guillaume et al. Cellular senescence in endothelial cells from atherosclerotic patients is accelerated by oxidative stress associated with cardiovascular risk factors. Mech envelhecimento. Mechanisms of Ageing and Development, v. 128, n. 11-12, p. 662-671, nov.-dec. 2007. Avaliable from: <https://www.sciencedirect.com/science/article

WANG, Julie et al. Vascular Smooth Muscle Cell Senescence Promotes Atherosclerosis and Features of Plaque Vulnerability. Circulation, v. 132, n. 20, p. 1909-1919, nov. 2015. Avaliable from: <http://circ.ahajournals.org/content/132/20/1909>. Access on 13 abr. 2018.

WEIBEL, Ewald and PALADE, George. New Cytoplasmic Components in Arterial Endothelia.The Journal of Cell Biology, Zurich, v. 23, n. 1, p. 101–112, oct. 1964. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106503/>. Access on 28 nov. 2017.

WEIBEL, Ewald and PALADE, George. New cytoplasmic components in the arterial endothelium. The Journal of Cell Biology, New York, v. 23, n. 1, p. 101-112, dec. 1964. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2106503/pdf/101.pdf>. Access on 22 nov. 2017.

WORLD HEALTH ORGANIZATION- WHO. Definitions and diagnossis of diabetes and intermediate hyperglycemia. Avaliable from: <http://apps.who.int/iris/bitstream/ha

WORLD HEALTH ORGANIZATION: Classification of atherosclerosis lesions. Report of a study group. Avaliable from: <http://apps.who.int/iris/handle/10665/40402>. Access on 13 abr. 2018.

XAPLANTERIS, Panagiotis and BRUYNE, Bernard. Angina pectoris: non-invasive methods in the diagnosis and follow-up. European Society of Cardiology, v.15, n.7, p. 1- 14, jun. 2017. Available from: <https://www.escardio.org/Journals/E-Journal-of-Cardiology-Practice/Volume-15/Angina-pectoris-non-invasive-methods-in-the-diagnosis

XAVIER, Hermes. et al. V Diretriz Brasileira de Dislipidemias e Prevenção da Aterosclerose. Arquivos Brasileiros de Cardiologia, v. 101, n. 4, p. 1-20, oct. 2013. Availablefrom:<http://www.scielo.br/scielo.php?script=sci_arttext&pid=S066782X20130041001&lng=en&nrm=iso>. Access on 21 mar. 2018.

YAN, Helen et al. Cross-talk between tight and anchoring junctions-lesson from the testis. Advances in experimental medicine and biology, v. 636, p. 234–54, jul. 2008. Avaliable from: <https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4080640/>. Access on 28 nov. 2017.

YANG, De-guang et al. Remnant-Like Lipoproteins May Accelerate Endothelial Progenitor Cells Senescence Through Inhibiting Telomerase Activity via the Reactive Oxygen Species-Dependent Pathway. Canadian Journal of Cardiology, v. 27, n. 5, p. 628–634, sept.-oct. 2011. Avaliable from: https://www.ncbi.nlm.nih.gov/pubmed/21764. Access on 30 feb. 2018.

Published

2019-03-18

How to Cite

RAYDAN, S. S. dos S. Estudo retrospectivo da incidência de fatores de risco em portadores da doença arterial coronariana / Retrospective study of the incidence of risk factors in carriers of coronary arterial disease. Brazilian Journal of Health Review, [S. l.], v. 2, n. 3, p. 1848–1917, 2019. Disponível em: https://ojs.brazilianjournals.com.br/ojs/index.php/BJHR/article/view/1506. Acesso em: 28 mar. 2024.

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Original Papers